Introduction - What is Mesothelioma?
Mesothelioma, a cancer of the lining of the lungs, chest and attacks the abdomen, is one of the most common cancers in the world today. This is a fatal, incurable disease reported - some statistics show that 9 will die in 10 patients with mesothelioma of the disease within 3 years. Only 5% survive more than 5 years after diagnosis.
Mesothelioma is caused by exposure to asbestos, a flexible,heat-resistant mineral fiber that was widely used in various sectors, including shipbuilding, construction and mining encountered. Since the link between asbestos and mesothelioma was found to have numerous actions by victims against the company filed for exposure. New laws to deal with asbestos came into force.
Since then, research on mesothelioma treatment capacity has continued, with variable results. Onenewer therapies is being investigated as anti-angiogenesis-based therapies.
Angiogenesis
The term "anti-angiogenesis" is derived from angiogenesis, a word that means the growth and development of new blood vessels. Such as cancer progress, soon outgrow the flow of blood through the blood vessels of the body available and need to grow its system of blood vessels to get an adequate supply of oxygen and nutrients. Without these new blood vessels, the cancer can not growand spread.
Anti-angiogenesis therapy Works
Anti-angiogenesis therapy is to prevent the cancer cells to grow new blood vessels, so as to slow or even stop the development of cancer. He does this by targeting the two chemicals in the body that regulate blood vessel growth: the growth factor basic fibroblast (FGF-2) and vascular endothelial growth factor (VEGF). The chemical pollution is very important for patients suffering from mesothelioma, tests havefound that people with mesothelioma showing VEGF levels much higher than those of patients with other types of cancer. These results suggest that mesothelioma may have a strong bond of VEGF, and thus may be better to treatments that VEGF target.
One tested the experimental drug against mesothelioma is bevacizumab. This medication is for use in patients with breast kidney, ovarian and testing in prostate cancer, among others.Currently, the results of one study) in 2005 until the end, and compared the efficacy of bevacizumab against two chemotherapy drugs (gemcitabine and cisplatin, which are reviewed and may not be issued.
If the anti-angiogenic therapy is a viable treatment or cure for mesothelioma it remains to be seen. Suffering While scientists find new ways to fight against mesothelioma, yet thousands of people from this devastating disease.
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